Gravitation, o'course. But there's only one bishounen (Yuki) and he's not one of the funny ones, so that doesn't quite match up.
Saiyuki. Roadtrip with constant bickering. Manga is prettier. Anime is sometimes funnier. But full of filler. I think the anime might pick back up during Reload (the "third season," kinda), but I haven't seen it yet, so I'm not sure.
If you haven't seen Trigun yet, by some miracle, DO IT NOW. This is not a drill.

But yeah, KKM without a doubt.